longterm effects of alcohol abuse
Behavioral Health & Substance Abuse

The Long-term Effects of Alcohol Abuse

Drinking alcohol to excess is harmful to your health.  Each year, from 2011 to 2015, alcohol abuse led to approximately 95,000 deaths and 2.8 million years of potential life lost.
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The Long-term Effects of Alcohol Abuse

If you visited your primary care physician recently, you were likely asked how many alcoholic beverages you drink in a week.  Did you tell the truth when you answered?  32% of women and 50% of men lie to their doctors about their alcohol consumption. *

Why does your doctor need to know? 

Physicians ask about your drinking because the amount and frequency of alcohol you consume produce significant effects on your overall health.

Your typical day includes a glass of wine or two with dinner.    During the weekend, you attend a social event during which you drink a couple of cocktails or more.   You never experience withdrawal symptoms when you stop drinking.  Your alcohol consumption hasn’t negatively affected your relationships.   You’re not an alcoholic, right?     

This may surprise you:

90% of excessive drinkers are not by definition alcoholics.  You do not need to be an alcoholic for alcohol to take a heavy toll on your health and cause serious social problems.  You also may not realize that alcohol (ethanol) is defined both as a drug and a toxin. 

Excessive alcohol consumption, according to the CDC, is responsible for 88,000 deaths per year and costs the U.S. more than $200 billion annually

What is considered “a drink?”

A “drink” or “alcoholic beverage” is defined as 5 ounces of wine, 12 ounces of beer, or 1.5 ounces of 80-proof distilled spirits.  These all have an identical level of alcohol.  It is a common misconception that wine, wine coolers, or even beer are not as dangerous as “hard” liquor.   For that reason, they may be more dangerous.

Whats a Drink Infographic: What's a Drink? 5 ounces of wine, 12 ounces of beer, or 1.5 ounces on liquor

How much alcohol is too much?

Alcohol Abuse Statistics

What are some problems caused by too much drinking?

Alcohol and the liver

The liver is a large organ located under the ribs on the right side of the body.  It filters waste, makes bile to digest food, stores sugar used for energy, and produces proteins that work throughout the body.  One of the important proteins causes blood to clot.   Persons with end-stage liver disease can bleed to death, especially from the abdomen.

Alcoholic liver disease is caused by the heavy use of alcohol. The liver’s job is to break down alcohol. If you drink more than it can process, it can become badly damaged.  Once it completely fails, it cannot heal.  You can’t live without your liver.

Alcoholic liver disease is common and preventable.  There are 3 types. Many heavy drinkers progress through all 3 types over time.


Fatty Liver

 The most common type of alcohol-induced liver disease is fatty liver.    Sometimes fatty liver does not cause symptoms, but it will often cause right-sided upper belly pain.  Weight loss, as well as fatigue and weakness, are common. 


Alcoholic Hepatitis

Alcoholic hepatitis is severe inflammation of the liver.  Liver cells die and cause permanent liver scarring.  This is caused by long-term alcohol abuse. Appetite loss and weakness are common.  People with hepatitis are acutely ill and have jaundice, yellowing of the skin and eyes.

hepatology liver

Alcoholic Cirrhosis

Alcoholic cirrhosis is the breakdown of healthy liver tissue.  This causes all of the symptoms of alcoholic hepatitis.   Poor nutrition, intestinal bleeding, fluid in the belly, kidney failure, and confusion occur.  This is irreversible liver failure.   Liver cancer often occurs with cirrhosis

The effects of alcohol on the liver depend on how much and how long you have been drinking alcohol. *

Head and neck cancer and alcohol

Drinking alcohol is one of the major risk factors for head and neck cancer (HNC) and causes approximately one-third of the cases worldwide. These cancers are in the throat, nose, sinus, and mouth. The more alcohol consumed, the more the risk for these cancers increase. Drinking alcoholic beverages, even for a short period, increases the risk of these cancers.   

 It’s different for oropharyngeal cancer.   This is a specific area behind the mouth in the middle of the throat.  How long alcohol is abused and how much has been consumed are both factors in developing this cancer. *

Breast Cancer and Alcohol

Exposure to alcohol increases a woman’s risk of hormone-related breast cancer. Alcohol can increase levels of estrogen and other hormones associated with hormone-receptor-positive breast cancer. 

Alcohol may increase breast cancer risk by damaging DNA in cells. Women who have three alcoholic drinks per week have a 15% higher risk of breast cancer. The risk of breast cancer goes up another 10% for each additional drink women regularly have each day.

Girls 9 to 15 who drink three to five drinks a week have three times the risk of developing benign breast lumps, which are associated with a higher risk of breast cancer later in life.

 Three to four alcoholic beverages per week increased the risk of breast cancer coming back in women who’d been diagnosed with early-stage disease. *

Your gastrointestinal tract

The GI tract (mouth, esophagus, stomach, small intestine, large intestine) is the first point of contact for most toxins entering the body, including alcohol.   We now know that poor GI health leads to overall poor body health, as damage to the GI tract causes an inflammatory response throughout the body.  

Alcohol, ingested chronically or in large amounts, causes inflammation.  The GI tract is likely the root of many of the worst consequences of excessive alcohol intake including chronic liver disease, neurological disease, a variety of cancers, and inflammatory bowel syndrome.

Alcohol, the gut, and the brain

Scientists have been aware for some time of the strong links between the gut and the brain.  They talk to each other; the brain helps to control the gut.  They now are beginning to realize the opposite is also true; the gut helps to control the brain.   

Changes in intestinal absorption caused by alcohol can affect cognition and behavior.  Cognition is the ability to process and understand information.  A study of patients undergoing alcohol detox had higher scores for depression, anxiety, and alcohol cravings and worse scores of attention and focus. 

Alcohol-induced gut inflammation can result in system-wide inflammation that affects nerve cell function and may cause many symptoms of alcohol withdrawal, including severe anxiety and disturbances in heart rate and blood pressure.

It is a myth that every alcoholic drink “kills brain cells.” Advances in imaging technology, however, allow researchers to see changes in structure and function in the brain that they previously could only guess.

Brains of alcoholics resemble the brains of significantly older alcoholics. The entire brain is more vulnerable to atrophy (shrinking) when excessive alcohol has been consumed for a long period of time.

The following areas of the brain are particularly susceptible to the negative effects of alcohol:

limbic system

The Limbic Sysyem

The limbic system (responsible for behavior and emotion) is negatively affected by heavy drinking.  Binge drinking and long-term drinking can damage the limbic system in a short period of time. This can increase the risk of dementia and decreased cognitive abilities. *

frontal lobe of brain

The Frontal Lobe

The frontal lobe (home of the personality) is the most vulnerable part of the brain to alcohol. The frontal lobe is responsible for cognition, thought, memory, and judgment. Alcohol use inhibits these functions.

right brain

The Right Hemisphere

 The right hemisphere (where spoken and written information is processed) is more susceptible to damage from alcohol than the left hemisphere (responsible for speech, comprehension, arithmetic, and writing). 

serotonin molecule


Neurotransmitters like dopamine and serotonin, are particularly sensitive to alcohol abuse. Neurotransmitters cause the transfer of nerve signals from one nerve to another. *

Drinking and birth defects

Much media attention and medical research addressed the dangers of drinking alcohol during pregnancy in the late 1970s and early 1980s. The problem remains 40 years later.  

Alcohol, even in small amounts causes catastrophic birth defects and lifetime disability.    Alcohol use during pregnancy causes birth defects and developmental disabilities known as fetal alcohol spectrum disorders (FASDs). 

 14% (1 in 7) of pregnant women reported current drinking or having at least one alcoholic beverage in the last 30 days.  One in twenty reported binge drinking (four or more drinks on one occasion) at least once in the past 30 days.  College-educated, employed, and unmarried pregnant people were more likely to report current drinking.

However, alcohol use among pregnant people was not higher in 2020 than in 2019, despite some evidence of increased alcohol sales and consumption among the general public during the COVID-19 pandemic.

Trauma and Alcohol

Every day, about 28 people in the United States die in drunk-driving crashes — that’s one person every 52 minutes. 10,142 people lost their lives. Those deaths were all preventable. *

Who should not consume alcohol

Moderate alcohol use isn’t free from risk. Remember that even light drinkers (those who have no more than one drink a day) have an increased risk of some cancers, such as esophageal and breast cancer.  Also, you just learned the statistics of alcohol involved driving and trauma. *

You don’t have to stop drinking completely if you aren’t able or don’t have the motivation.  Even cutting down on your consumption of alcohol will benefit your health.  Some of the negative effects on your body, especially your GI system and brain, can lessen or even resolve over time.

Suggestions for limiting alcohol intake

No need to feel overwhelmed if you have decided to cut down on your drinking.  Cutting down is not “all or nothing.”  Changing habits take some time, but it is best accomplished in small steps.

If you have trouble limiting the amount of alcohol that you consume, you may have Alcohol Use Disorder (AUD).  Our Alcohol Use Disorder Self Test can help you determine if you meet the criteria.  If you find that you are not able to overcome the temptation to drink alcohol to excess, there are a number of resources available to you.

Please reach out to New Method Wellness if you would like more information about alcohol and drug addiction treatment.


  1. What patients lie to their doctors about, and why | British Columbia Medical Journal. (2021). The British Columbia Medical Journal. https://bcmj.org/news/what-patients-lie-their-doctors-about-and-why
  2. Drinking Levels Defined. (2021). National Institute on Alcohol Abuse and Alcoholism (NIAAA). https://www.niaaa.nih.gov/alcohol-health/overview-alcohol-consumption/moderate-binge-drinking
  3. https://www.npr.org/sections
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  5. Credico, D. G. (2020, August 24). Alcohol drinking and head and neck cancer risk: the joint effect of intensity and duration. Nature. https://www.nature.com/articles/s41416-020-01031/
  6. https://pubmed.ncbi.nlm.nih.gov/
  7. Breast Cancer Risk Factors. (2018). Breastcancer.Org. https://www.breastcancer.org/risk/risk-factors
  8. Drinking Levels Defined. (2019). National Institute on Alcohol Abuse and Alcoholism (NIAAA). https://www.niaaa.nih.gov/alcohol-health/overview-alcohol-consumption/moderate-binge-drinking
  9. Alcoholic liver disease. (2022). National Library of Medicine. https://medlineplus.gov/ency/article/000281.htm
  10. Alcohol use and binge drinking among pregnant adults in the US. (2022, January 6). Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/fasd/features/alcohol-use-and-binge-drinking.html
  11. Alcohol use: Weighing risks and benefits. (2021, December 11). Mayo Clinic. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/alcohol/art-20044551?reDate=1103202
  12. Alcoholic Liver Disease. (2020). Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/alcoholinduced-liver-disease
  13. Impaired Driving: Get the Facts. (2020). Centers For Disease Control and Safety. https://www.cdc.gov/transportationsafety/impaired_driving/impaired-drv_factsheet.html
  14. Statement on Insurance, Alcohol-Related Injuries, and Trauma Centers. (2006). American College of Surgeons. https://www.facs.org/about-acs/statements/55-alcohol-trauma
  15. Oscar-Berman, Marlene (June 2003). “Alcoholism and the Brain”Alcohol Research & Health. https://pubmed.ncbi.nlm.nih.gov/15303622/
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